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Article: Gene-based mapping and pathway analysis of metabolic traits in dairy cows.

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Ha NT; Gross JJ; van Dorland A; Tetens J; Thaller G; Schlather M; Bruckmaier R; Simianer H
PLoS ONE, 2015


10.1371/journal.pone.0122325.t003 The 5 pathways with the smallest p-values according to the WKST and WRST for the joined analysis of the NEFA, BHBA and glucose measurements at T2 and T2/T1.
Time Rank WKST P-Value (WKST) WRST P-Value (WRST)
T2 1 Steroid hormone biosynthesis 0.0018 Steroid hormone biosynthesis 0.0040
T2 2 Retinol metabolism 0.0063 Other glycan degradation 0.0199
T2 3 Drug metabolism-other enzymes 0.0115 Drug metabolism-cytochrome P450 0.0222
T2 4 Starch and sucrose metabolism 0.0124 Retinol metabolism 0.0223
T2 5 Other glycan degradation 0.0174 Starch and sucrose metabolism 0.0242
T2/T1 1 Ether lipid metabolism 0.0030 Glycerophospholipid metabolism 0
T2/T1 2 Glycerophospholipid metabolism 0.0034 Ether lipid metabolism 5.00E-04
T2/T1 3 Other glycan degradation 0.0061 Nitrogen metabolism 0.0028
T2/T1 4 Tyrosine metabolism 0.0113 Tyrosine metabolism 0.0151
T2/T1 5 Nitrogen metabolism 0.0144 Other glycan degradation 0.0174

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